Noninvasive Dentistry: A Dream or Reality?

Caries Res. 2015;49 Suppl 1:11-7. doi: 10.1159/000380887. Epub 2015 Apr 13.


Various caries prevention and repair strategies are reviewed in this article ranging from the use of fluoride to nanohydroxyapatite particles. Several of the strategies which combine fluoride and calcium and phosphate treatments have both in vitro and in vivo data showing them to be efficacious if the surface integrity of the lesion is not breached. Once this has occurred, the rationale for cutting off the nutrient supplies to the pathogenic bacteria without the removal of the infected dentine, a noninvasive restorative technique, is discussed using existing clinical studies as examples. Finally two novel noninvasive restorative techniques using fluorohydroxyapatite crystals are described. The need for clinical data in support of emerging caries-preventive and restorative strategies is emphasized.

Publication types

  • Review

MeSH terms

  • Calcium Phosphates / therapeutic use
  • Cariostatic Agents / therapeutic use
  • Dental Caries / prevention & control*
  • Dental Caries / therapy
  • Dental Restoration, Permanent / methods
  • Durapatite / therapeutic use
  • Fluorides / therapeutic use
  • Humans
  • Hydroxyapatites / therapeutic use
  • Nanoparticles / therapeutic use
  • Tooth Remineralization / methods


  • Calcium Phosphates
  • Cariostatic Agents
  • Hydroxyapatites
  • fluorohydroxyapatite
  • Durapatite
  • calcium phosphate
  • Fluorides