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. 2015 Mar 6;5(1):85-95.
doi: 10.1159/000365506. eCollection Jan-Apr 2015.

Use of the MoCA in Detecting Early Alzheimer's Disease in a Spanish-Speaking Population With Varied Levels of Education

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Free PMC article

Use of the MoCA in Detecting Early Alzheimer's Disease in a Spanish-Speaking Population With Varied Levels of Education

Yan Zhou et al. Dement Geriatr Cogn Dis Extra. .
Free PMC article

Abstract

Background/aims: Performance on the Montreal Cognitive Assessment (MoCA) has been demonstrated to be dependent on the educational level. The purpose of this study was to identify how to best adjust MoCA scores and to identify MoCA items most sensitive to cognitive decline in incipient Alzheimer's disease (AD) in a Spanish-speaking population with varied levels of education.

Methods: We analyzed data from 50 Spanish-speaking participants. We examined the pattern of diagnosis-adjusted MoCA residuals in relation to education and compared four alternative score adjustments using bootstrap sampling. Sensitivity and specificity analyses were performed for the raw and each adjusted score. The interval reliability of the MoCA as well as item discrimination and item validity were examined.

Results: We found that with progressive compensation added for those with lower education, unexplained residuals decreased and education-residual association moved to zero, suggesting that more compensation was necessary to better adjust MoCA scores in those with a lower educational level. Cube copying, sentence repetition, delayed recall, and orientation were most sensitive to cognitive impairment due to AD.

Conclusion: A compensation of 3-4 points was needed for <6 years of education. Overall, the Spanish version of the MoCA maintained adequate psychometric properties in this population.

Keywords: Alzheimer's disease; Dementia; Education; Hispanic population; Latino population; Mild cognitive impairment; Montreal Cognitive Assessment; Screening; Spanish-speaking population.

Figures

Fig. 1
Fig. 1
Scatter plot of diagnosis-adjusted MoCA residuals and years of education. The solid line is the zero reference line, and the dashed line represents the best fit regression line.

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References

    1. Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Chertkow H. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53:695–699. - PubMed
    1. Chertkow H, Nasreddine Z, Johns E, Phillips N, McHenry C. The Montreal Cognitive Assessment (MoCA): validation of alternate forms and new recommendations for education corrections. Alzheimers Dement. 2011;7:S157.
    1. Bernstein IH, Lacritz L, Barlow CE, Weiner MF, DeFina LF. Psychometric evaluation of the Montreal Cognitive Assessment (MoCA) in three diverse samples. Clin Neuropsychol. 2011;25:119–126. - PubMed
    1. Rossetti HC, Lacritz LH, Cullum CM, Weiner MF. Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample. Neurology. 2011;77:1272–1275. - PubMed
    1. Wu Y, Wang M, Ren M, Xu W. The effects of educational background on Montreal Cognitive Assessment screening for vascular cognitive impairment, no dementia, caused by ischemic stroke. J Clin Neurosci. 2013;20:1406–1410. - PubMed
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