Osteomalacia, severe thoracic deformities and respiratory failure in a young woman with anorexia nervosa

Intern Med. 2015;54(8):929-34. doi: 10.2169/internalmedicine.54.3673. Epub 2015 Apr 15.

Abstract

The recent trends in avoiding sunbathing and eating fewer fish products have resulted in a high prevalence of vitamin D deficiency in the general Japanese population. We herein report the case of a young woman with enduring anorexia nervosa (AN) who suffered from osteomalacia, thoracic deformities and respiratory failure. Her vitamin D deficiency had been overlooked for years. Although the serum 25-hyroxyvitamin D [25(OH)D] level is a marker of vitamin D stores, it is not routinely examined because the cost is not covered by the national health insurance program. However, measuring the serum 25(OH)D levels in AN patients with hypocalcemia is recommended to prevent osteomalacia and osteoporosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anorexia Nervosa / complications*
  • Anorexia Nervosa / metabolism
  • Anorexia Nervosa / physiopathology
  • Bone Density Conservation Agents / therapeutic use*
  • Calcium Compounds / therapeutic use*
  • Female
  • Humans
  • Hydroxycholecalciferols / therapeutic use*
  • Lactates / therapeutic use*
  • Osteomalacia / drug therapy
  • Osteomalacia / etiology*
  • Osteomalacia / metabolism
  • Osteomalacia / physiopathology
  • Prevalence
  • Respiratory Insufficiency / etiology*
  • Respiratory Insufficiency / physiopathology
  • Treatment Outcome
  • Vitamin D / blood
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / complications*

Substances

  • Bone Density Conservation Agents
  • Calcium Compounds
  • Hydroxycholecalciferols
  • Lactates
  • Vitamin D
  • calcium lactate
  • alfacalcidol