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. 2015 Apr 16;520(7547):307-11.
doi: 10.1038/nature14397.

A Resource for Cell Line Authentication, Annotation and Quality Control

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A Resource for Cell Line Authentication, Annotation and Quality Control

Mamie Yu et al. Nature. .

Abstract

Cell line misidentification, contamination and poor annotation affect scientific reproducibility. Here we outline simple measures to detect or avoid cross-contamination, present a framework for cell line annotation linked to short tandem repeat and single nucleotide polymorphism profiles, and provide a catalogue of synonymous cell lines. This resource will enable our community to eradicate the use of misidentified lines and generate credible cell-based data.

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