Molecular dynamics of Staphylococcus aureus nasal carriage in Hajj pilgrims

P O Verhoeven; P Gautret; C H Haddar; S Benkouiten; J Gagnaire; K Belhouchat; F Grattard; R Charrel; B Pozzetto; T Drali; F Lucht; P Brouqui; Z A Memish; P Berthelot; E Botelho-Nevers

doi:10.1016/j.cmi.2015.03.020

Molecular dynamics of Staphylococcus aureus nasal carriage in Hajj pilgrims

Clin Microbiol Infect. 2015 Jul;21(7):650.e5-8. doi: 10.1016/j.cmi.2015.03.020. Epub 2015 Apr 13.

Authors

P O Verhoeven¹, P Gautret², C H Haddar³, S Benkouiten², J Gagnaire⁴, K Belhouchat², F Grattard¹, R Charrel², B Pozzetto¹, T Drali², F Lucht⁵, P Brouqui², Z A Memish⁶, P Berthelot⁷, E Botelho-Nevers⁸

Affiliations

¹ GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France; Laboratory of Infectious Agents and Hygiene, University Hospital of Saint-Etienne, Saint-Etienne, France.
² Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095 and Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.
³ Laboratory of Infectious Agents and Hygiene, University Hospital of Saint-Etienne, Saint-Etienne, France.
⁴ GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France.
⁵ GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France; Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.
⁶ Public Health Directorate, Saudi Ministry of Health, World Health Organization Collaborating Centre for Mass Gathering Medicine and College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia.
⁷ GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France; Laboratory of Infectious Agents and Hygiene, University Hospital of Saint-Etienne, Saint-Etienne, France; Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.
⁸ GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France; Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France. Electronic address: e.botelhonevers@gmail.com.

PMID: 25882367
DOI: 10.1016/j.cmi.2015.03.020

Abstract

During the 2012 Hajj season, the risk of acquisition of Staphylococcus aureus nasal carriage in a cohort of French pilgrims was 22.8%, and was statistically associated with the acquisition of viral respiratory pathogens (p 0.03). The carriage of S. aureus belonging to the emerging clonal complex 398 significantly increased following the pilgrimage (p < 0.05).

Keywords: Carriage acquisition; Hajj; Staphylococcus aureus carriage; overcrowding; respiratory viruses.

MeSH terms

Adult
Aged
Carrier State / epidemiology*
Cohort Studies
Crowding*
Female
France
Humans
Male
Middle Aged
Nasal Mucosa / microbiology*
Religion
Saudi Arabia
Staphylococcal Infections / epidemiology*
Staphylococcal Infections / transmission
Staphylococcus aureus / isolation & purification*
Travel