Association between betapapillomavirus seropositivity and keratinocyte carcinoma-prospects for prophylactic vaccination?

J Invest Dermatol. 2015 May;135(5):1211-1213. doi: 10.1038/jid.2014.523.


In this issue, Genders et al. (2015) demonstrate in a cohort of organ transplant recipients that betapapillomavirus seropositivity around transplantation significantly increases the risk of developing keratinocyte carcinomas. These results further substantiate an etiologic role of betapapillomaviruses in skin cancer and raise prospects of anti-viral immunotherapy.

Publication types

  • Comment

MeSH terms

  • Antibodies, Viral / blood*
  • Betapapillomavirus / immunology*
  • Female
  • Humans
  • Keratinocytes / pathology*
  • Kidney Transplantation*
  • Male
  • Pancreas Transplantation*
  • Skin Neoplasms / epidemiology*
  • Transplant Recipients*


  • Antibodies, Viral