Keeping gut lining at bay: impact of emulsifiers

Trends Endocrinol Metab. 2015 Jun;26(6):273-4. doi: 10.1016/j.tem.2015.03.009. Epub 2015 Apr 14.

Abstract

Obesity is associated with altered gut microbiota and low-grade inflammation. Both dietary habits and food composition contribute to the onset of such diseases. Emulsifiers, compounds commonly used in a variety of foods, were shown to induce body weight gain, low-grade inflammation and metabolic disorders. These dietary compounds promote gut microbiota alteration and gut barrier dysfunction leading to negative metabolic alterations.

Keywords: colitis; emuslifiers; gut microbiota; inflammation; mucus; obesity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Food Additives / adverse effects*
  • Gastrointestinal Tract / drug effects*
  • Gastrointestinal Tract / immunology*
  • Gastrointestinal Tract / microbiology
  • Humans
  • Inflammation / chemically induced
  • Microbiota / drug effects
  • Obesity / chemically induced

Substances

  • Food Additives