Ratiometric sensing of lysine through the formation of the pyrene excimer: experimental and computational studies

Chem Commun (Camb). 2015 May 18;51(40):8536-9. doi: 10.1039/c5cc01359c.

Abstract

Several pyrene based fluorescent probes undergo lysine assisted monomer to excimer conversion in a ratiometric manner. Intracellular lysine is detected using fluorescence microscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Amines / chemistry
  • Fluorescent Dyes* / chemistry
  • Fluorescent Dyes* / pharmacology
  • Lysine* / analysis
  • Lysine* / chemistry
  • Lysine* / metabolism
  • MCF-7 Cells
  • Microscopy, Fluorescence
  • Pyrenes* / chemistry
  • Pyrenes* / pharmacology

Substances

  • Aldehydes
  • Amines
  • Fluorescent Dyes
  • Pyrenes
  • pyrene
  • Lysine