The iceLogo web server and SOAP service for determining protein consensus sequences

Nucleic Acids Res. 2015 Jul 1;43(W1):W543-6. doi: 10.1093/nar/gkv385. Epub 2015 Apr 20.


The iceLogo web server and SOAP service implement the previously published iceLogo algorithm. iceLogo builds on probability theory to visualize protein consensus sequences in a format resembling sequence logos. Peptide sequences are compared against a reference sequence set that can be tailored to the studied system and the used protocol. As such, not only over- but also underrepresented residues can be visualized in a statistically sound manner, which further allows the user to easily analyse and interpret conserved sequence patterns in proteins. The web application and SOAP service can be found free and open to all users without the need for a login on

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Amino Acid Sequence
  • Animals
  • Consensus Sequence*
  • Internet
  • Mice
  • Sequence Analysis, Protein / methods*
  • Software*