[Isolation of pomolic acid from Chamaenerion angustifolium and evaluation of its genotoxicity by microbiological tests]

Bioorg Khim. Jan-Feb 2014;40(1):92-8. doi: 10.1134/s1068162013060046.
[Article in Russian]

Abstract

Fireweed (Chamaenerion angustifolium) lipophilic constituents were investigated by GC-MS analysis. 28 aliphatic and 6 triterpenic acids were found out at first time. Pomolic acid genotoxicity and mutagenicity were analyzed by Ames test and SOS chromotest. Genotoxic and mutagenic properties of pomolic acid were not detected.

MeSH terms

  • Escherichia coli / drug effects
  • Escherichia coli / genetics
  • Gas Chromatography-Mass Spectrometry
  • Mutagenicity Tests / methods*
  • Mutagens / toxicity
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / isolation & purification
  • Oleanolic Acid / toxicity
  • Onagraceae / chemistry*
  • SOS Response, Genetics / drug effects
  • Salmonella typhimurium / drug effects
  • Salmonella typhimurium / genetics

Substances

  • Mutagens
  • pomolic acid
  • Oleanolic Acid