tEMPting Fate MaYBe the Solution

Immunity. 2015 Apr 21;42(4):597-9. doi: 10.1016/j.immuni.2015.04.001.

Abstract

In the present issue of Immunity, Hoeffel et al. (2015) reconcile a controversy by demonstrating that a distinct wave of yolk-sac-derived erythro-myeloid progenitors (EMPs) differentiate to fetal monocytes in the liver and further to adult macrophages in the majority of tissues.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Aging / immunology*
  • Animals
  • Female
  • Macrophages / immunology*
  • Monocytes / immunology*
  • Myeloid Progenitor Cells / immunology*
  • Pregnancy
  • Proto-Oncogene Proteins c-myb / immunology*

Substances

  • Proto-Oncogene Proteins c-myb