Successful management of chronic high-output ileostomy with high dose loperamide

BMJ Case Rep. 2015 Apr 22;2015:bcr2015209411. doi: 10.1136/bcr-2015-209411.

Abstract

High-stoma output is a common problem that can lead to dehydration and electrolyte disturbance. The following report describes three patients with end ileostomy who had high-stoma outputs where conventional medical management was unsuccessful in controlling stoma output. All three patients responded to high-dose loperamide, resulting in significant clinical improvement. High-dose loperamide therapy should be considered in patients with high-stoma output who have failed conventional medical management.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Antidiarrheals / administration & dosage*
  • Chronic Disease
  • Dehydration
  • Diarrhea / drug therapy*
  • Diarrhea / etiology
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Feces
  • Female
  • Humans
  • Ileostomy* / adverse effects
  • Intestinal Diseases / complications
  • Intestinal Diseases / drug therapy
  • Intestinal Diseases / surgery*
  • Loperamide / administration & dosage*
  • Male
  • Treatment Outcome
  • Water-Electrolyte Imbalance / etiology*

Substances

  • Antidiarrheals
  • Loperamide