Abstract
We propose the hypothesis that the benefits of exercise on inflammation in cancer are a result of a direct effect on inflammatory cytokines, including interleukin-6, tumor necrosis factor-α, and monocyte chemoattractant protein 1, that are critical for cancer growth as well as a bystander effect of the established relationship between exercise and cancer.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Animals
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Breast Neoplasms / physiopathology
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Chemokine CCL2 / metabolism
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Colonic Neoplasms / physiopathology
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Cytokines / physiology*
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Exercise / physiology*
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Humans
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Inflammation / physiopathology*
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Interleukin-6 / metabolism
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Neoplasms / immunology
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Neoplasms / physiopathology*
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Tumor Necrosis Factor-alpha / metabolism
Substances
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Chemokine CCL2
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Cytokines
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IL6 protein, human
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Interleukin-6
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TNF protein, human
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Tumor Necrosis Factor-alpha