Benign chondroblastoma on fine-needle aspiration smears: A seven-case experience and review of the literature

Diagn Cytopathol. 2015 Sep;43(9):734-8. doi: 10.1002/dc.23286. Epub 2015 Apr 25.

Abstract

We report seven cases of chondroblastoma (CB) of bone, diagnosed by Fine-Needle Aspiration Cytology (FNAC), and confirmed by histomorphological examination. The concurrence of some cytomorphologic findings - mononucleated cells, multinucleated cells, and intercellular chondroid substance - unequivocally suggested the cytological diagnosis of CB. We also reviewed the literature on this topic in order to discuss morphological criteria and the importance of needle size. The differential diagnosis between CB, Giant Cell Tumor of Bone, and Eosinophilic Granuloma is further discussed.

Keywords: bone cytology; bone tumors; chondroblastoma; fine-needle aspiration cytology.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Biopsy, Fine-Needle
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / pathology
  • Bone and Bones / pathology
  • Child
  • Chondroblastoma / diagnosis*
  • Chondroblastoma / pathology
  • Female
  • Giant Cell Tumors / diagnosis
  • Giant Cell Tumors / pathology
  • Giant Cells / cytology*
  • Humans
  • Male
  • Retrospective Studies
  • Young Adult