Iridoids and a norsesquiterpenoid from the leaves of Villaria odorata

Nat Prod Commun. 2014 Sep;9(9):1229-30.


Phytochemical investigation of Villaria odorata, a Philippine endemic Rubiaceae species, led to the identification of three iridoids, morindolide (1), hydrophylin A (2), hydrophylin B (3) and a norsesquiterpenoid, vomifoliol (4). This is the first report of compounds 1-4 from the genus Villaria. These classes of compounds proved to be important chemotaxonomic markers in the Rubiaceae family in combination with morphology and molecular data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Iridoids / chemistry*
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Leaves / chemistry*
  • Rubiaceae / chemistry*
  • Sesquiterpenes / chemistry*


  • Iridoids
  • Plant Extracts
  • Sesquiterpenes