Why patients with severe personality disorders are overmedicated

J Clin Psychiatry. 2015 Apr;76(4):e521. doi: 10.4088/JCP.14com09441.


Emotionally unstable personality disorder (EUPD), more widely known as borderline personality disorder (BPD), has long been considered a clinical challenge. Patients meeting criteria for these diagnoses are emotionally dysregulated, impulsive, and involved in troubled relationships; in clinical settings, they may threaten suicide or attempt it and are frequently seen in emergency departments. Patients with BPD can be treatment resistant, even when clinically depressed, to both pharmacotherapy and standard types of psychotherapy.

Publication types

  • Comment

MeSH terms

  • Affective Symptoms / drug therapy*
  • Affective Symptoms / epidemiology*
  • Borderline Personality Disorder / drug therapy*
  • Borderline Personality Disorder / epidemiology*
  • Drug Utilization / statistics & numerical data*
  • Female
  • Humans
  • Male
  • Mental Health Services / statistics & numerical data*
  • Personality Disorders / drug therapy*
  • Personality Disorders / epidemiology*
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Psychotropic Drugs / therapeutic use*
  • State Medicine / statistics & numerical data*


  • Psychotropic Drugs