Theories of aging: an ever-evolving field

Acta Naturae. 2015 Jan-Mar;7(1):9-18.


Senescence has been the focus of research for many centuries. Despite significant progress in extending average human life expectancy, the process of aging remains largely elusive and, unfortunately, inevitable. In this review, we attempted to summarize the current theories of aging and the approaches to understanding it.

Keywords: accumulation of damage; advanced glycation end-product; aging; life expectancy; reactive oxygen species; telomerase.