No increase in prevalence of somatization in functional vs organic dyspepsia: a cross-sectional survey

Neurogastroenterol Motil. 2015 Jul;27(7):1024-31. doi: 10.1111/nmo.12578. Epub 2015 Apr 30.

Abstract

Background: Psychological factors are associated with functional gastrointestinal (GI) disorders. Literature suggests that somatization is associated with functional dyspepsia (FD). However, the relationship between organic dyspepsia (OD), FD, and FD subtypes and somatization is poorly described. We aimed to examine this issue in a cross-sectional study of secondary care patients.

Methods: Demographic and GI symptom data were collected from 4224 adult patients via the Rome III questionnaire. Somatization data were collected using the patient health questionnaire-12. Mean somatization score and number of somatic symptoms were compared between patients with organic and FD, and between FD subtypes using analysis of variance. The same comparison was undertaken for the proportion of patients reporting individual somatic symptoms.

Key results: Exactly, 783 patients met criteria for dyspepsia, of whom 231 (29.5%) had organic disease following upper GI endoscopy. Mean somatization scores and number of somatic symptoms were no higher in functional vs OD (p = 0.23; p = 0.19). In addition, while the prevalence of somatization in FD was relatively high, there was no difference in severity of somatization in FD subgroups.

Conclusions & inferences: Somatization is associated with functional and OD to the same degree. Overall severity of somatization did not appear to vary according to FD subtype.

Keywords: epigastric pain; postprandial distress; somatization; symptom severity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Cross-Sectional Studies
  • Dyspepsia / epidemiology*
  • Dyspepsia / physiopathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Somatoform Disorders / epidemiology*
  • Somatoform Disorders / physiopathology
  • Surveys and Questionnaires
  • Young Adult