Increasing Trend in Emergency Department Visits for Hypoglycemia From Patients With Type 2 Diabetes Mellitus in Taiwan

Prim Care Diabetes. 2015 Dec;9(6):490-6. doi: 10.1016/j.pcd.2015.04.002. Epub 2015 Apr 27.

Abstract

Aims: We analyze the time trends of hypoglycemia-related emergency department visits in Taiwan between 2000 and 2010, focusing on type 2 diabetic patients receiving antidiabetic agents.

Methods: From a national dataset containing longitudinal medical claims of one million persons, we ascertained 4479 hypoglycemia-related emergency department visits from 3184 type 2 diabetic patients for analysis. We used negative binomial regression to calculate the incidence rate ratios (IRRs) for comparing event rates of hypoglycemia-related emergency department visits in different study periods.

Results: Rates of hypoglycemia-related emergency department visits increased 4.8 folds from year 2000 to 2010 (adjusted IRR 4.88, 95% CI 3.94-6.05, P<0.001). Severe hypoglycemia requiring emergency department visits prevailed among women, older patients (≥ 65 years), and those not lived in the urban areas.

Conclusions: Within a 10-year period, there was a substantial increase in the rates of hypoglycemia-related emergency department visits from type 2 diabetic patients in Taiwan. Appropriate risk management plans should be developed to prevent the occurrence of severe hypoglycemia in patients with type 2 diabetes in Taiwan.

Keywords: Emergency department; Hypoglycemia; Incidence; Type 2 diabetes.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Blood Glucose / drug effects*
  • Blood Glucose / metabolism
  • Databases, Factual
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Emergency Service, Hospital / statistics & numerical data
  • Emergency Service, Hospital / trends*
  • Female
  • Humans
  • Hypoglycemia / blood
  • Hypoglycemia / chemically induced*
  • Hypoglycemia / diagnosis
  • Hypoglycemia / epidemiology
  • Hypoglycemia / therapy
  • Hypoglycemic Agents / adverse effects*
  • Incidence
  • Male
  • Middle Aged
  • Residence Characteristics
  • Risk Factors
  • Sex Factors
  • Taiwan / epidemiology
  • Time Factors

Substances

  • Biomarkers
  • Blood Glucose
  • Hypoglycemic Agents