Injections for chronic pain

Phys Med Rehabil Clin N Am. 2015 May;26(2):249-61. doi: 10.1016/j.pmr.2015.01.004.


Although interventional procedures should be used cautiously in the setting of chronic pain, there is a role for a variety of injections to facilitate a patient's overall rehabilitation program. There are many resources available, including a prior issue of Physical Medicine and Rehabilitation Clinics of North America, which discuss the more conventional spinal injections. The focus of this article is on lesser-known injection options for treating chronic pain. The authors separately discuss trigger point injections, regenerative injections (prolotherapy), and injections using botulin toxins.

Keywords: Botulinum toxins; Chronic pain; Regenerative injections; Trigger point injections.

Publication types

  • Review

MeSH terms

  • Analgesia, Epidural
  • Botulinum Toxins / therapeutic use
  • Chronic Pain / drug therapy*
  • Humans
  • Injections*
  • Pain Management
  • Pain Measurement
  • Trigger Points
  • Zygapophyseal Joint


  • Botulinum Toxins