HLA class I antigens in severe RSV bronchiolitis

Tissue Antigens. 1989 Sep;34(3):210-2. doi: 10.1111/j.1399-0039.1989.tb01740.x.

Abstract

Cytotoxic T-lymphocytes (CTL) recognize virus-infected cells in association with HLA class I antigens. There is strong evidence of the importance of CTL in respiratory syncytial virus (RSV) infections. We looked for but were unable to demonstrate an association between particular HLA class I antigens and severe RSV bronchiolitis in infants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bronchiolitis, Viral / immunology*
  • Child
  • Disease Susceptibility
  • HLA Antigens / analysis*
  • HLA-A Antigens / analysis
  • HLA-B Antigens / analysis
  • Humans
  • Infant
  • Respiratory Syncytial Viruses
  • Respirovirus Infections / immunology*

Substances

  • HLA Antigens
  • HLA-A Antigens
  • HLA-B Antigens