PsyGeNET: A Knowledge Platform on Psychiatric Disorders and Their Genes

Bioinformatics. 2015 Sep 15;31(18):3075-7. doi: 10.1093/bioinformatics/btv301. Epub 2015 May 11.


PsyGeNET (Psychiatric disorders and Genes association NETwork) is a knowledge platform for the exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of a database and a web interface supporting data search, visualization, filtering and sharing. PsyGeNET integrates information from DisGeNET and data extracted from the literature by text mining, which has been curated by domain experts. It currently contains 2642 associations between 1271 genes and 37 psychiatric disease concepts. In its first release, PsyGeNET is focused on three psychiatric disorders: major depression, alcohol and cocaine use disorders. PsyGeNET represents a comprehensive, open access resource for the analysis of the molecular mechanisms underpinning psychiatric disorders and their comorbidities.

Availability and implementation: The PysGeNET platform is freely available at The PsyGeNET database is made available under the Open Database License (


Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcoholism / genetics*
  • Algorithms
  • Animals
  • Biomarkers / analysis*
  • Chromosome Mapping
  • Cocaine-Related Disorders / genetics*
  • Data Mining
  • Databases, Factual
  • Depressive Disorder, Major / genetics*
  • Disease Models, Animal
  • Gene Regulatory Networks*
  • Humans
  • Knowledge Bases*
  • Mice
  • Publications
  • Rats
  • Software*


  • Biomarkers