Visual field damage in normal-tension and high-tension glaucoma

Am J Ophthalmol. 1989 Dec 15;108(6):636-42. doi: 10.1016/0002-9394(89)90854-4.


We studied the ocular characteristics of 40 pairs of normal-tension and high-tension glaucoma patients who matched closely for the extent of field damage, pupil size, and visual acuity. To determine if there were differences in visual field damage between patients with normal-tension and high-tension glaucoma, we studied characteristics of the areas of the patients' visual fields that were undisturbed. We computed the number of normal locations, the number of clustered normal locations, and the size of the largest cluster of normal locations. The results showed that for an equivalent extent of damage, the individuals in the normal-tension group had greater areas with normal sensitivity, hence more localized damage. A comparison of the patient data to control data showed that paired differences were larger when the normal-tension member of a pair had a larger value in any of the parameters. The results support the hypothesis that glaucoma patients with lower intraocular pressures have more localized damage and those with higher intraocular pressures have more diffuse damage.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Female
  • Glaucoma / physiopathology*
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Ocular Hypertension / physiopathology*
  • Visual Field Tests
  • Visual Fields*