Ocular Lyme borreliosis

Am J Ophthalmol. 1989 Dec 15;108(6):651-7. doi: 10.1016/0002-9394(89)90856-8.


In six patients with ocular Lyme borreliosis, bilateral granulomatous iridocyclitis and vitritis were present in five. One of these five also had bilateral optic neuritis. Another patient developed combined trochlear and facial nerve palsies. A syndrome resembling pars planitis with atypical features such as granulomatous keratic precipitates and posterior synechiae should prompt a search for Lyme borreliosis. Topical corticosteroid therapy is necessary to prevent complications of anterior segment inflammation caused by Lyme uveitis, but the benefit of systemic and periocular corticosteroids is uncertain. Oral antibiotics may be effective in treating early stages of ocular Lyme borreliosis. In later stages, intravenous antibiotic therapy is indicated.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Enzyme-Linked Immunosorbent Assay
  • Eye Infections, Parasitic / diagnosis
  • Eye Infections, Parasitic / drug therapy
  • Eye Infections, Parasitic / etiology*
  • Female
  • Humans
  • Iridocyclitis / diagnosis
  • Iridocyclitis / drug therapy
  • Iridocyclitis / etiology
  • Lyme Disease / diagnosis*
  • Lyme Disease / drug therapy
  • Male
  • Optic Neuritis / diagnosis
  • Optic Neuritis / drug therapy
  • Optic Neuritis / etiology
  • Visual Acuity
  • Vitreous Body / physiopathology


  • Adrenal Cortex Hormones
  • Anti-Bacterial Agents