Effects of line type blood-liquid warmer on two different infusion sets

J Pak Med Assoc. 2015 Apr;65(4):362-5.

Abstract

Objective: To investigate the source of 'bubbles' in infusion sets which were caused by the 'line type' blood-liquid warmers used in operation rooms to prevent hypothermia.

Methods: The experimental study was conducted from August to September 2012 at the Thoracic Surgery Department of Dokuz Eylul University, Izmir, Turkey, by warming liquids in the operation room experimentally in a setting similar to clinical routine. Initially, 0.9% sodium chloride solution was infused using S-line blood-liquid warmers with Medisetin patients who were placed in Group M). The IPC Group had Intrafix Primeline Confortset at a rate of 350ml/hour in the operating room. The initiation time and level of bubble formation, temperatures of the operation room, infusion liquid, S-line device, line of the device, and the liquid at the outflow were recorded. Data was analysed with SPSS 15.

Results: The two groups had 10 subjects each. The temperatures of the working area, the liquid before and after being placed in the warming device, the proximal-middle and distal parts of the line and the set temperature on the screen of the device were similar and the difference between them was not statistically significant (p>0.05). While no bubble formation was observed in Group IPC, bubbles were formed after 9.80±0.78 minutes and the level of bubble formation was close to 3 in Group Mediset (2.80±1.03). The main difference between the two groups was di (2-ethylhexyl) phthalate content of Mediset.

Conclusions: Infusion sets containing di(2-ethylhexyl) phthalate should not be used with warming devices in order to avoid toxic effects.

Keywords: Blood-liquid warmer, Infusion set, Bubbles, Di(2-ethylhexyl)phthalate..

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Blood Transfusion / instrumentation*
  • Blood Transfusion / methods
  • Diethylhexyl Phthalate / pharmacology
  • Embolism, Air* / etiology
  • Embolism, Air* / prevention & control
  • Equipment Design
  • Humans
  • Hypothermia* / etiology
  • Hypothermia* / prevention & control
  • Infusions, Intravenous / instrumentation*
  • Infusions, Intravenous / methods
  • Plasticizers / pharmacology
  • Rewarming* / instrumentation
  • Rewarming* / methods
  • Risk Assessment
  • Surgical Procedures, Operative / methods
  • Surgical Procedures, Operative / standards
  • Temperature
  • Treatment Outcome

Substances

  • Plasticizers
  • Diethylhexyl Phthalate