Evaluation and management of head and neck squamous cell carcinoma of unknown primary

Jeffrey M Martin; Thomas J Galloway

doi:10.1016/j.soc.2015.03.007

Evaluation and management of head and neck squamous cell carcinoma of unknown primary

Surg Oncol Clin N Am. 2015 Jul;24(3):579-91. doi: 10.1016/j.soc.2015.03.007. Epub 2015 Apr 11.

Authors

Jeffrey M Martin¹, Thomas J Galloway²

Affiliations

¹ Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
² Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA. Electronic address: Thomas.galloway@fccc.edu.

PMID: 25979401
DOI: 10.1016/j.soc.2015.03.007

Abstract

The diagnostic evaluation and therapeutic management of a patient with squamous cell carcinoma of an unknown primary (SCCUP) has considerably evolved over recent decades and will likely continue to change as a result of the improving ability to identify small primary tumors and better tailor the implementation of multimodality therapy. By application of the general principles of head and neck oncology, physicians and surgeons are often able to achieve satisfactory control of the disease in patients with SCCUP.

Keywords: Head and neck cancer; Radiation therapy; Squamous cell carcinoma; Surgery; Unknown primary.

Publication types

Evaluation Study
Review

MeSH terms

Carcinoma, Squamous Cell / therapy*
Combined Modality Therapy
Disease Management
Head and Neck Neoplasms / therapy*
Humans
Neoplasms, Unknown Primary / therapy*
Prognosis