Cancers of major salivary glands

Aru Panwar; Jessica A Kozel; William M Lydiatt

doi:10.1016/j.soc.2015.03.011

Cancers of major salivary glands

Surg Oncol Clin N Am. 2015 Jul;24(3):615-33. doi: 10.1016/j.soc.2015.03.011.

Authors

Aru Panwar¹, Jessica A Kozel², William M Lydiatt³

Affiliations

¹ Division of Head and Neck Surgery, University of Nebraska Medical Center, 600 S, 42nd Street, Omaha, NE 68198, USA. Electronic address: aru.panwar@unmc.edu.
² Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
³ Division of Head and Neck Surgery, Nebraska Methodist Hospital, 8303 Dodge Street, Omaha, NE 68114, USA.

PMID: 25979403
DOI: 10.1016/j.soc.2015.03.011

Abstract

Major salivary gland malignancies are a rare but histologically diverse group of entities. Establishing the diagnosis of a malignant salivary neoplasm may be challenging because of the often minimally symptomatic nature of the disease, and limitations of imaging modalities and cytology. Treatment is centered on surgical therapy and adjuvant radiation in selected scenarios. Systemic therapy with chemotherapeutic agents and monoclonal antibodies lacks evidence in support of its routine use.

Keywords: Cancer; Malignancy; Neoplasm; Salivary glands.

Publication types

Review

MeSH terms

Combined Modality Therapy
Humans
Prognosis
Salivary Gland Neoplasms / pathology*
Salivary Gland Neoplasms / therapy*