ADVISE: First Results of a European Interoperative Information System Network Developed for the ADenoVirus Initiative Study in Epidemiology

Stud Health Technol Inform. 2015;210:675-7.


Adenoviral conjunctivitis is extremely contagious, causes a form of conjunctivitis. Therefore, it is important to identify patients who suffer from adenoviral conjunctivitis, as early as possible, in order to contain the disease. We present the 6 independent but interoperable platforms developed for the purpose of a large European epidemiologic study (ADVISE), which has been implemented independently in France, Germany, Spain, Italy and the UK. ADVISE is a non-interventional, observational epidemiology study with the objectives of assessing clinical characteristics and incidence of adenovirus conjunctivitis. One of the challenges faced in developing this network of European epidemiology platforms has been the multilingual context. Actually, we have established independent platforms fully dedicated to each of the participating countries. Similar protocols have been submitted across these countries, allowing individual and pooled analyses of the data. A standardized questionnaire is used to collect patient ocular medical history. The electronic questionnaire contains 151 items with automatic coherence control. The first platform ADVISE was set up in France. Development, evaluation and validation of this platform were carried out between January and July 2013. The Medical Informatics and Knowledge Engineering Laboratory (LIMICS), proposes through this project, a tool that allows the installation and application of epidemiologic monitoring in any part of the world.

MeSH terms

  • Adenoviridae Infections
  • Conjunctivitis, Viral
  • Electronic Health Records / organization & administration*
  • Europe / epidemiology
  • European Union / organization & administration*
  • Forms and Records Control
  • Health Information Systems / organization & administration*
  • Humans
  • Information Storage and Retrieval / methods*
  • Medical Record Linkage / methods*
  • Pilot Projects
  • Population Surveillance / methods*
  • Prevalence
  • Risk Assessment / methods