Importance of Both Fatness and Aerobic Fitness on Metabolic Syndrome Risk in Japanese Children

PLoS One. 2015 May 20;10(5):e0127400. doi: 10.1371/journal.pone.0127400. eCollection 2015.


Associations between body mass index (BMI), peak oxygen consumption (VO(2peak)), and metabolic syndrome (MetS) risk factors have not been adequately studied in Japanese children. Here the relationships between these parameters and the threshold aerobic fitness level necessary for low MetS risk were determined. The participants (299 children; 140 boys and 159 girls, aged 9.1 ± 0.3 years) were divided into four groups using the medians of predicted VO(2peak) (pVO(2peak)) and BMI. MetS risk scores were calculated using z-scores. Receiver Operating Characteristic analysis was used to determine the threshold aerobic fitness level necessary for low MetS risk. The MetS risk score of the High BMI group was significantly higher than that of the Low BMI group for both sexes (p < 0.0001). However, the High BMI/High Fitness group had a significantly lower MetS risk score than the High BMI/Low Fitness group for both sexes. The (p)VO(2peak )cut-off values for low MetS risk were 47.9 and 44.9 ml/kg/min for boys and girls, respectively. Our results suggest that improvements in both fatness and aerobic fitness are important for decreasing MetS risk. We also confirmed the (p)VO(2peak) of cut-off values necessary for low MetS risk in Japanese children.

MeSH terms

  • Adiposity*
  • Asian Continental Ancestry Group*
  • Body Mass Index
  • Child
  • Exercise*
  • Female
  • Humans
  • Japan / epidemiology
  • Male
  • Metabolic Syndrome / epidemiology*
  • Metabolic Syndrome / physiopathology*
  • Oxygen Consumption
  • Physical Fitness*
  • ROC Curve
  • Risk Factors

Grant support

The authors received no specific funding for this work.