Factors Affecting the Outcomes of Uncomplicated Primary Open Ankle Arthrodesis

Foot Ankle Int. 2015 Oct;36(10):1170-9. doi: 10.1177/1071100715587045. Epub 2015 May 20.

Abstract

Background: The objective of this study was to identify factors influencing operative outcomes in straightforward, uncomplicated open ankle fusions.

Methods: We reviewed all primary open ankle fusions conducted at 1 institution over an 11-year period to identify straightforward, uncomplicated open ankle fusions. Inclusion required a minimum of 6 months follow-up. Patients were excluded for neuropathic arthropathy, insensate limb, failed total ankle replacement, simultaneous arthrodesis of the subtalar joint, or fusions performed within 1 year of injury to salvage failed fixation and painful function due to (1) open fractures, (2) segmental bone loss greater than 1 cm, (3) infection, or (4) talar body fractures. The primary outcome variable was radiographic union at 6 months. Other operative complications were analyzed as secondary outcomes. Five hundred twenty-eight ankle fusion surgeries were performed on 440 patients at 1 institution during the study period. Two hundred fifteen surgeries met inclusion/exclusion eligibility criteria for uncomplicated open ankle fusions.

Results: The overall union rate was 91%. In this cohort of uncomplicated open ankle fusions, bivariate analysis over a broad range of potential factors and further focused multivariate analysis found that nonunion was more than 3 times more likely to occur after previous subtalar fusion, and 2 times more likely to occur in patients with preoperative varus ankle alignment. The rate of reoperation was 19%, with nonunion revision as the leading reason, followed by hardware removal and incision and drainage for presumed infection. Diabetes was not a significant risk factor of either deep or superficial infection.

Conclusion: Open ankle fusion failed in 9% of uncomplicated ankles with arthritis. Patients who had an open ankle fusion done after previous subtalar joint fusion, as well as those who had preoperative varus ankle alignment, had a significantly higher rate of nonunion.

Level of evidence: Level III, retrospective comparative study.

Keywords: ankle arthrodesis; ankle fusion; ankle nonunion; subtalar fusion.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Analysis of Variance
  • Ankle Joint / diagnostic imaging
  • Ankle Joint / physiopathology
  • Ankle Joint / surgery*
  • Arthrodesis / adverse effects
  • Arthrodesis / methods*
  • Body Mass Index
  • Cohort Studies
  • Comorbidity
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Osteoarthritis / diagnostic imaging
  • Osteoarthritis / surgery*
  • Osteoporosis / diagnosis
  • Osteoporosis / epidemiology
  • Postoperative Complications / physiopathology
  • Postoperative Complications / surgery
  • Radiography
  • Regression Analysis
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Sex Factors
  • Time Factors
  • Treatment Outcome