Abstract
A ruthenium-catalyzed oxidative coupling of 2-aryl-quinazolinones with olefins via C-H bond activation followed by an intramolecular aza-Michael reaction is described. This strategy allows the direct and efficient construction of pyrrolo[2,1-b]quinazolin-9(1H)-one scaffolds.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry*
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Catalysis
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Chemistry Techniques, Synthetic
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Oxidative Coupling*
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Quinazolinones / chemical synthesis*
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Quinazolinones / chemistry
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Ruthenium / chemistry*
Substances
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Alkenes
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Quinazolinones
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Ruthenium