Bats as reservoirs of severe emerging infectious diseases

Virus Res. 2015 Jul 2:205:1-6. doi: 10.1016/j.virusres.2015.05.006. Epub 2015 May 18.

Abstract

In recent years severe infectious diseases have been constantly emerging, causing panic in the world. Now we know that many of these terrible diseases are caused by viruses originated from bats (Table 1), such as Ebola virus, Marburg, SARS coronavirus (SARS-CoV), MERS coronavirus (MERS-CoV), Nipah virus (NiV) and Hendra virus (HeV). These viruses have co-evolved with bats due to bats' special social, biological and immunological features. Although bats are not in close contact with humans, spillover of viruses from bats to intermediate animal hosts, such as horses, pigs, civets, or non-human primates, is thought to be the most likely mode to cause human infection. Humans may also become infected with viruses through aerosol by intruding into bat roosting caves or via direct contact with bats, such as catching bats or been bitten by bats.

Keywords: Bat; Ebola; Emerging infectious diseases; Hendra; MERS; Natural reservoir; Nipah; SARS; Viruses.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Chiroptera / virology*
  • Communicable Diseases, Emerging / transmission
  • Communicable Diseases, Emerging / virology*
  • Disease Reservoirs / virology*
  • Humans
  • Virus Diseases / transmission
  • Virus Diseases / virology*
  • Viruses / classification
  • Viruses / genetics
  • Viruses / isolation & purification*