The role of cardiovascular magnetic resonance in sudden death risk stratification in hypertrophic cardiomyopathy

Martin S Maron

doi:10.1016/j.ccep.2015.03.003

The role of cardiovascular magnetic resonance in sudden death risk stratification in hypertrophic cardiomyopathy

Card Electrophysiol Clin. 2015 Jun;7(2):187-93. doi: 10.1016/j.ccep.2015.03.003.

Author

Martin S Maron¹

Affiliation

¹ Division of Cardiology, Hypertrophic Cardiomyopathy Center, Tufts Medical Center, #70, 800 Washington Street, Boston, MA 02111, USA. Electronic address: mmaron@tuftsmedicalcenter.org.

PMID: 26002385
DOI: 10.1016/j.ccep.2015.03.003

Abstract

Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden death in young patients, but current risk stratification strategies do not identify all patients at risk. Contrast-enhanced cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) can identify areas of abnormal myocardial substrate comprising fibrosis, the structural nidus for potentially life-threatening ventricular arrhythmias. More recently, follow-up studies have demonstrated a strong relationship between extent of LGE in patients with HCM and increased risk of adverse disease-related events, including sudden death.

Keywords: Cardiovascular magnetic resonance; Hypertrophic cardiomyopathy; Late gadolinium enhancement; Myocardial fibrosis; Sudden death.

Publication types

Review

MeSH terms

Cardiomyopathy, Hypertrophic*
Death, Sudden, Cardiac*
Endomyocardial Fibrosis
Humans
Magnetic Resonance Imaging, Cine*