Somatostatin Receptors in an Anaplastic Oligodendroglioma Relapse Evidenced By 68Ga DOTANOC PET/CT

Clin Nucl Med. 2015 Jul;40(7):e363-5. doi: 10.1097/RLU.0000000000000816.


Six years ago, a right frontal lobe anaplastic oligodendroglioma negative for AE1/AE3 and HBM-45, positive for 1p/19q deletion, EMA, GFAP, and synaptophysin was excised from a 50-year-old woman. Treatments that followed were radiation therapy, and surgery plus radiation therapy and temozolomide for a relapse with an early partial response, followed by disease progression. In the middle of last year, ⁶⁸Ga-DOTANOC PET/CT was carried out to evaluate the possibility of treatment with peptide receptor radionuclide therapy. The examination revealed a grossly round-shaped uptake corresponding to the surgical wall, with some smaller uptakes disseminated in different parts of the brain.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / genetics
  • Female
  • Gene Deletion
  • Humans
  • Middle Aged
  • Multimodal Imaging
  • Oligodendroglioma / diagnostic imaging*
  • Oligodendroglioma / genetics
  • Organometallic Compounds*
  • Positron-Emission Tomography*
  • Radiopharmaceuticals*
  • Tomography, X-Ray Computed*


  • 68Ga-DOTANOC
  • Organometallic Compounds
  • Radiopharmaceuticals