Food Allergy in Childhood (Infancy to School Age)

Chem Immunol Allergy. 2015;101:38-50. doi: 10.1159/000371666. Epub 2015 May 21.

Abstract

Food allergy is a potentially life-threatening condition affecting almost 10% of children, with an increasing incidence in the last few decades. It is defined as an immune reaction to food, and its pathogenesis may be IgE mediated, mixed IgE and non-IgE mediated, or non-IgE mediated. Potentially all foods can cause food allergy, but a minority of foods are responsible for the vast majority of reactions reported. A good clinical history is crucial for an accurate diagnosis. Allergy tests, including the skin prick test and measurement of specific IgE antibodies, are useful tools in the case of IgE-mediated or mixed allergy but have not been shown to be of any help in delayed allergic reactions to foods.

MeSH terms

  • Amelogenesis Imperfecta / complications
  • Amelogenesis Imperfecta / epidemiology
  • Amelogenesis Imperfecta / immunology
  • Animals
  • Child, Preschool
  • Dietary Proteins / adverse effects
  • Dietary Proteins / immunology
  • Enterocolitis / complications
  • Enterocolitis / epidemiology
  • Enterocolitis / immunology
  • Food Hypersensitivity / complications
  • Food Hypersensitivity / diagnosis*
  • Food Hypersensitivity / epidemiology*
  • Food Hypersensitivity / immunology
  • Hearing Loss, Sensorineural / complications
  • Hearing Loss, Sensorineural / epidemiology
  • Hearing Loss, Sensorineural / immunology
  • Humans
  • Immunoglobulin E / immunology
  • Infant
  • Milk / adverse effects
  • Milk / immunology
  • Nails, Malformed / complications
  • Nails, Malformed / epidemiology
  • Nails, Malformed / immunology
  • Proctocolitis / complications
  • Proctocolitis / epidemiology
  • Proctocolitis / immunology
  • Skin Tests

Substances

  • Dietary Proteins
  • Immunoglobulin E

Supplementary concepts

  • Deafness enamel hypoplasia nail defects