Peanut and tree nut allergy

Chem Immunol Allergy. 2015;101:131-44. doi: 10.1159/000375417. Epub 2015 May 21.


Allergy to peanut and tree nuts is a major worldwide health concern. The prevalence of these allergies may be increasing, but the reasons for these increases remain unclear. This group of foods accounts for a large proportion of severe and fatal food-allergic reactions. These allergies present most often during childhood but can occur at any age. Resolution is possible but uncommon, and frequent lifetime reactions caused by accidental ingestion are a serious problem. The major allergens of peanut and most tree nuts have been identified, allowing for insights into patient diagnoses, clinical outcomes, and potential future immunotherapies.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Age Factors
  • Allergens / adverse effects
  • Allergens / immunology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunoglobulin E / immunology
  • Immunotherapy
  • Infant
  • Nut Hypersensitivity / diagnosis*
  • Nut Hypersensitivity / epidemiology*
  • Nut Hypersensitivity / immunology
  • Nut Hypersensitivity / therapy
  • Peanut Hypersensitivity / diagnosis*
  • Peanut Hypersensitivity / epidemiology*
  • Peanut Hypersensitivity / immunology
  • Peanut Hypersensitivity / therapy


  • Allergens
  • Immunoglobulin E