Microwave Ablation Compared to Radiofrequency Ablation for Hepatic Lesions: A Meta-Analysis

J Vasc Interv Radiol. 2015 Aug;26(8):1139-1146.e2. doi: 10.1016/j.jvir.2015.04.004. Epub 2015 May 28.


To evaluate the efficacy and safety of microwave (MW) ablation compared with radiofrequency (RF) ablation for hepatic lesions by using meta-analytic techniques. Overall, 16 studies involving 2,062 patients were included. MW ablation was found to have significantly better 6-year overall survival than RF ablation (odds ratio, 1.64, 95% confidence interval, 1.15-2.35), but this was based on a few articles (n = 3 of 16). MW ablation and RF ablation had similar 1-5-year overall survival, disease-free survival, local recurrence rate, and adverse events. Based on similar safety and efficacy outcomes, either MW ablation or RF ablation may be used for effective local hepatic therapy.

Publication types

  • Comparative Study
  • Multicenter Study
  • Review

MeSH terms

  • Aged
  • Catheter Ablation / mortality*
  • Female
  • Humans
  • Incidence
  • Liver Neoplasms / mortality*
  • Liver Neoplasms / surgery*
  • Male
  • Microwaves / therapeutic use*
  • Middle Aged
  • Neoplasm Recurrence, Local / mortality*
  • Neoplasm Recurrence, Local / prevention & control*
  • Risk Factors
  • Survival Rate
  • Treatment Outcome