Burkitt lymphoma with unusual presentation: Acute pancreatitis

Pediatr Int. 2015 Aug;57(4):775-7. doi: 10.1111/ped.12640. Epub 2015 May 29.

Abstract

Pancreatitis due to malignant infiltration is an uncommon condition in childhood. Pancreatic lymphomas constitute <2% of all non-Hodgkin lymphomas. Only six reported cases with various clinical presentation have been documented in the literature. Described herein is the case of a nine-year-old boy with abdominal pain, jaundice, emesis, weight loss, diarrhea, who developed hyperlipidemia and cholestasis. Pancreatitis was suspected due to high amylase and lipase. Computed tomography and magnetic resonance cholangiopancreatography showed diffuse enlargement of the pancreas. This sausage pancreas imaging was suggestive of autoimmune pancreatitis, but the patient was diagnosed with Burkitt lymphoma on bone marrow aspiration, and rapidly improved with chemotherapy. Burkitt lymphoma should be kept in mind when patients present with pancreatitis, especially with diffuse enlarged pancreas.

Keywords: burkitt lymphoma; children; pancreatitis.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Burkitt Lymphoma / diagnosis*
  • Burkitt Lymphoma / drug therapy
  • Child
  • Cholangiopancreatography, Magnetic Resonance
  • Humans
  • Male
  • Pancreatitis / diagnosis*
  • Pancreatitis / drug therapy
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents