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. 2015 Aug;93(2):384-9.
doi: 10.4269/ajtmh.15-0196. Epub 2015 Jun 1.

Jamestown Canyon Virus Disease in the United States-2000-2013

Daniel M Pastula  1 , Diep K Hoang Johnson  1 , Jennifer L White  1 , Alan P Dupuis 2nd  1 , Marc Fischer  1 , J Erin Staples  2
Affiliations

Jamestown Canyon Virus Disease in the United States-2000-2013

Daniel M Pastula et al. Am J Trop Med Hyg. 2015 Aug.

Abstract

Jamestown Canyon virus (JCV) is a mosquito-borne orthobunyavirus in the California serogroup that can cause an acute febrile illness, meningitis, or meningoencephalitis. We describe epidemiologic and clinical features for JCV disease cases occurring in the United States during 2000-2013. A case of JCV disease was defined as an acute illness in a person with laboratory evidence of a recent JCV infection. During 2000-2013, we identified 31 cases of JCV disease in residents of 13 states. The median age was 48 years (range, 10-69) and 21 (68%) were male. Eleven (35%) case patients had meningoencephalitis, 6 (19%) meningitis, 7 (23%) fever without neurologic involvement, and 7 (23%) had an unknown clinical syndrome. Fifteen (48%) were hospitalized and there were no deaths. Health-care providers and public health officials should consider JCV disease in the differential diagnoses of viral meningitis and encephalitis, obtain appropriate specimens for testing, and report cases to public health authorities.

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Figures

Figure 1.
Figure 1.
Jamestown Canyon virus disease cases by year of illness onset, United States, 2000–2013.
Figure 2.
Figure 2.
Jamestown Canyon virus disease cases by month of illness onset, United States, 2000–2013.
Figure 3.
Figure 3.
Jamestown Canyon virus disease cases by state of residence, United States, 2000–2013. There were no cases from Alaska or Hawaii.
See this image and copyright information in PMC

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