[Syphilis and pregnancy]

Presse Med. 2015 Jun;44(6 Pt 1):631-8. doi: 10.1016/j.lpm.2015.04.011. Epub 2015 May 29.
[Article in French]


Syphilis is a sexually transmitted disease responsible for a congenital severe infection. Congenital syphilis is complicated by fetal loss/neonatal death (50%), prematurity (25%) and major long term sequelae in other surviving children (20%). Every woman delivering a stillborn after 20WG should be tested for syphilis. Early screening is the cornerstone of prevention, and should be repeated in women at higher risk of contamination. Maternal management relies on early benzathine penicillin administration. Neonatal management relies on early diagnosis and prompt adequate penicillin therapy.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Female
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnancy Complications, Infectious / microbiology*
  • Syphilis* / diagnosis
  • Syphilis* / drug therapy
  • Syphilis* / transmission