[Preretinal hemorrhage and prognosis following vitrectomy and silicone oil tamponade for severe proliferative diabetic retinopathy]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Mar;44(2):167-73. doi: 10.3785/j.issn.1008-9292.2015.03.008.
[Article in Chinese]

Abstract

Objective: To examine the prognosis of preretinal hemorrhage following vitrectomy and silicone oil tamponade for severe proliferative diabetic retinopathy.

Methods: Clinical data of 76 cases of proliferative diabetic retinopathy treated with vitrectomy and silicone oil infusion tamponade in Sir Run Run Shaw Hospital from October 2006 to September 2013 were retrospectively reviewed. Intraoperative bleeding,postoperative preretinal bleeding,blood reabsorption time, and preretinal fibrosis were assessed.

Results: All preretinal hemorrhage developed within 1 week after surgery, blood was distributed in thin and scattered patterns (32 cases), thick and localized patterns (25 cases) or thick and scattered patterns (19 cases). The preretinal hemorrhage was ceased in 1 day after operation in 35 cases, in 2 days after operation in 18 cases, in two weeks after operation in 23 case. Recurrent hemorrhage occurred within 1 week after operation in 15 cases. Thin blood was largely reabsorbed in about two weeks, and thick blood was largely reabsorbed in about five weeks. Fibrosis tissue was resulted in 15 cases(34.1%) with thick blood.

Conclusion: Most of preretinal hemorrhage occurs within 1 week after surgery and is reabsorpted with 5 weeks in patients with proliferative diabetic retinopathy undergoing vitrectomy and silicone oil tamponade. The major complication of preretinal bleeding is the formation of preretinal fibrosis.

目的: 观察分析重度增殖性糖尿病视网膜病变(PDR)患者玻璃体切除硅油填充术后视网膜前出血程度及其转归。

方法: 收集2006年10月至2013年9月在浙江大学医学院附属邵逸夫医院因重度PDR需行玻璃体切除硅油填充术的76眼76例患者(其中术前使用抗血管内皮生长因子41例)的临床资料;回顾性分析患者玻璃体切除硅油填充术中出血量、术后视网膜前出血的量、出血吸收时间和术后视网膜前增殖的程度及其之间的关系。

结果: 患者术后视网膜前出血均发生于术后1周内,其中32例出现较薄、散在的出血;25例出现较厚、局灶性的出血;19例出现较厚、散在的出血。35例出血于术后1天停止;18例于术后2天内停止;余23例于术后2周内停止,其中包括15例1周内出现复发性出血患者。较薄出血者2周、较厚出血者5周左右出血基本吸收。15例(34.1%)较厚出血吸收后形成增殖膜。

结论: 重度PDR患者玻璃体切除硅油填充术后1周内均会出现不同程度出血,5周左右可以吸收。较厚较多的出血患者常并发视网膜前纤维增殖膜形成。

MeSH terms

  • Diabetic Retinopathy / surgery*
  • Fibrosis
  • Humans
  • Postoperative Complications*
  • Prognosis
  • Retrospective Studies
  • Silicone Oils / therapeutic use
  • Vitrectomy*
  • Vitreous Hemorrhage / epidemiology*

Substances

  • Silicone Oils

Grants and funding

浙江省公益技术研究社会发展项目(2011C23019)