Neurofibromatosis type 2

William H Slattery

doi:10.1016/j.otc.2015.02.005

Neurofibromatosis type 2

Otolaryngol Clin North Am. 2015 Jun;48(3):443-60. doi: 10.1016/j.otc.2015.02.005.

Author

William H Slattery¹

Affiliation

¹ House Clinic, 2100 West 3rd Street, Suite 111, Los Angeles, CA 90057, USA. Electronic address: wslattery@hei.org.

PMID: 26043141
DOI: 10.1016/j.otc.2015.02.005

Abstract

Neurofibromatosis type 2 (NF2) is a rare syndrome characterized by bilateral vestibular schwannomas, multiple meningiomas, cranial nerve tumors, spinal tumors, and eye abnormalities. NF2 presents unique challenges to the otologist because hearing loss may be the presenting complaint leading to the diagnosis of the disorder. Care of patients with NF2 requires knowledge of all tumors and symptoms involved with the disorder. It is recommended that patients receive care in a center with expertise in NF2. The role of the neuro-otologist in this care is determined by the specialty center.

Keywords: Acoustic neuroma; Neurofibromatosis type 2; Vestibular schwannoma.

Publication types

Review

MeSH terms

Genes, Neurofibromatosis 2
Health Knowledge, Attitudes, Practice
Hearing Loss / etiology
Humans
Magnetic Resonance Imaging
Meningeal Neoplasms / complications*
Meningioma / complications*
Neurofibromatosis 2 / genetics
Neurofibromatosis 2 / pathology*
Neurofibromatosis 2 / therapy*