Acute colonic pseudo-obstruction in pregnancy

ANZ J Surg. 2015 Oct;85(10):728-33. doi: 10.1111/ans.13201. Epub 2015 Jun 4.

Abstract

Background: Acute colonic pseudo-obstruction is an uncommon but potentially morbid complication of pregnancy. The aim of the study was to review a single institution's experience with acute colonic pseudo-obstruction in post-partum patients and develop an algorithm for management based on a literature review.

Methods: This is a retrospective study where patients were identified over a 2-year period (1 December 2012 to 31 November 2014) by checking all deliveries in Christchurch Women's Hospital against diagnosis codes for bowel obstruction and ileus. Clinical records and radiology were then reviewed to identify those with acute colonic pseudo-obstruction and the management of these patients was reviewed.

Results: Over the study period, seven patients were identified from 10,240 deliveries. Two patients required laparotomy and the rest resolved without surgical intervention. One patient was treated with neostigmine and three with erythromycin. One patient had an unsuccessful attempt at endoscopic decompression, however, symptoms resolved without further intervention following this. A management algorithm was developed based on the literature review.

Conclusions: Acute colonic pseudo-obstruction occurs in post-partum patients more frequently than suspected (one in 1500 deliveries). The management needs to be active with early correction of electrolyte abnormalities, avoidance of narcotic pain relief and early mobilization. Timely administration of neostigmine or endoscopic decompression can reduce the incidence of colonic ischaemia and perforation and the need for surgical intervention.

Keywords: Ogilvie's syndrome; cesarean section; colonic pseudo-obstruction; pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / diagnosis
  • Abdominal Pain / diagnostic imaging
  • Acute Disease
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Cesarean Section / methods
  • Colonic Pseudo-Obstruction / diagnosis*
  • Colonic Pseudo-Obstruction / physiopathology
  • Colonic Pseudo-Obstruction / surgery*
  • Decompression, Surgical / methods
  • Erythromycin / therapeutic use
  • Female
  • Humans
  • Intestinal Obstruction / diagnosis
  • Intestinal Obstruction / physiopathology
  • Intestinal Obstruction / surgery*
  • Laparotomy / methods
  • Neostigmine / therapeutic use
  • Parasympathomimetics / therapeutic use
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Pregnancy Complications / physiopathology
  • Pregnancy Complications / surgery*
  • Radiography
  • Retrospective Studies
  • Tomography Scanners, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Parasympathomimetics
  • Neostigmine
  • Erythromycin