Three Decades of High-Dose Nicotine Gum Dependence Treated With Nicotine Patches

Nicotine Tob Res. 2016 May;18(5):1220-1. doi: 10.1093/ntr/ntv124. Epub 2015 Jun 4.


Introduction: Some long-term nicotine gum users are addicted to nicotine and may need assistance to stop. There is no published evidence on the use of nicotine patches for this purpose.

Case description: A 45-year old man presented with a 30-year history of high-dose nicotine gum use (up to 200mg nicotine per day). He was highly nicotine dependent and had failed repeatedly to stop using nicotine gum use in the past. Within a week of commencing nicotine patches he was able to cease nicotine gum with minimal discomfort and has remained nicotine-free for 6 months, with abstinence confirmed biochemically. His severe sweating disorder rapidly resolved with cessation of the gum.

Conclusion: Nicotine patches may be an effective treatment for long-term nicotine gum addiction.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Humans
  • Male
  • Middle Aged
  • Nicotine / administration & dosage*
  • Nicotine / adverse effects
  • Smoking / drug therapy*
  • Smoking / psychology
  • Smoking / urine
  • Smoking Cessation / methods*
  • Smoking Cessation / psychology
  • Time Factors
  • Tobacco Use Cessation Devices*
  • Tobacco Use Disorder / drug therapy*
  • Tobacco Use Disorder / psychology
  • Tobacco Use Disorder / urine


  • Nicotine