Plasma 19-hydroxyandrostenedione and androstenedione levels in hydatidiform moles and early pregnancies with and without hypertensive diseases

Aust N Z J Obstet Gynaecol. 1989 Aug;29(3 Pt 1):238-41. doi: 10.1111/j.1479-828x.1989.tb01727.x.

Abstract

Because of the association of preeclampsia with hydatidiform mole, and since levels of 19-hydroxyandrostenedione (19-OH-A) and androstenedione (A) are raised in hypertensive diseases of pregnancy, we compared plasma 19-OH-A and A in hydatidiform mole patients with control early pregnant women. Both steroids were significantly elevated in 27 patients with partial or complete hydatidiform moles, as compared with the levels in 36 control pregnancies at similar stages of gestation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Androstenedione / analogs & derivatives*
  • Androstenedione / blood*
  • Female
  • Humans
  • Hydatidiform Mole / blood*
  • Hydatidiform Mole / complications
  • Hypertension / blood*
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / blood*
  • Uterine Neoplasms / blood*
  • Uterine Neoplasms / complications

Substances

  • Androstenedione
  • 19-hydroxy-4-androstene-3,17-dione