Long-term Follow-up of Positive Surgical Margins in Basal Cell Carcinoma of the Face

Dermatol Surg. 2015 Jul;41(7):761-7. doi: 10.1097/DSS.0000000000000394.

Abstract

Background: Basal cell carcinoma (BCC) in central facial locations and tumors with positive margins are at a higher risk of recurrence. The most effective treatment is total excision, which includes an adequate pathological margin.

Objective: To evaluate the outcome of the patients who underwent surgery for BCCs of the head and neck and of those who had positive surgical margins where Mohs surgery is not available.

Methods: This study was conducted at Ege University Medical School between 2004 and 2014. One hundred thirty patients with 154 BCC who underwent surgical excision were included. In the histopathologic report, the existence of positive margin, BCC subtype, localization of the tumor, and distance of margins to the tumor were evaluated.

Results: Twenty-three lesions (14.9%) of 22 patients revealed positive surgical margins. Six patients (26.1%) had recurrences on the surgical site. The BCC subtypes of recurrent patients were reported to be multifocal superficial in 2 (33.3%), infiltrative (16.7%) in 1, and micronodular (50%) in 3.

Conclusion: Patients with superficial multifocal or micronodular tumors should undergo reoperation because of high recurrence rates.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Basal Cell Carcinoma / epidemiology
  • Basal Cell Carcinoma / pathology
  • Basal Cell Carcinoma / surgery*
  • Female
  • Follow-Up Studies
  • Head and Neck Neoplasms / epidemiology
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / surgery*
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Recurrence, Local / surgery
  • Reoperation / statistics & numerical data
  • Retrospective Studies
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery*
  • Treatment Outcome
  • Turkey / epidemiology