Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms

Dev Cell. 2015 Jun 8;33(5):496-7. doi: 10.1016/j.devcel.2015.05.015.


Reporting in Developmental Cell, Hara and Merten (2015) apply the use of microfabrication and in vitro analysis in cell-free extracts to the old problem of nuclear size control. The authors make insights into the regulation of nuclear growth that potentially explain the widely reported correlation between nucleus size and cell size.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Nucleus / physiology*
  • Dyneins / metabolism*
  • Female
  • Microtubules / metabolism*
  • Nuclear Envelope / physiology*
  • Oocytes / cytology*
  • Oocytes / metabolism*
  • Xenopus laevis / metabolism*


  • Dyneins