Electrical Brain Responses to an Auditory Illusion and the Impact of Musical Expertise

PLoS One. 2015 Jun 12;10(6):e0129486. doi: 10.1371/journal.pone.0129486. eCollection 2015.

Abstract

The presentation of two sinusoidal tones, one to each ear, with a slight frequency mismatch yields an auditory illusion of a beating frequency equal to the frequency difference between the two tones; this is known as binaural beat (BB). The effect of brief BB stimulation on scalp EEG is not conclusively demonstrated. Further, no studies have examined the impact of musical training associated with BB stimulation, yet musicians' brains are often associated with enhanced auditory processing. In this study, we analysed EEG brain responses from two groups, musicians and non-musicians, when stimulated by short presentation (1 min) of binaural beats with beat frequency varying from 1 Hz to 48 Hz. We focused our analysis on alpha and gamma band EEG signals, and they were analysed in terms of spectral power, and functional connectivity as measured by two phase synchrony based measures, phase locking value and phase lag index. Finally, these measures were used to characterize the degree of centrality, segregation and integration of the functional brain network. We found that beat frequencies belonging to alpha band produced the most significant steady-state responses across groups. Further, processing of low frequency (delta, theta, alpha) binaural beats had significant impact on cortical network patterns in the alpha band oscillations. Altogether these results provide a neurophysiological account of cortical responses to BB stimulation at varying frequencies, and demonstrate a modulation of cortico-cortical connectivity in musicians' brains, and further suggest a kind of neuronal entrainment of a linear and nonlinear relationship to the beating frequencies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Auditory Cortex / physiology*
  • Brain Waves
  • Case-Control Studies
  • Evoked Potentials, Auditory*
  • Female
  • Humans
  • Illusions*
  • Male
  • Music*

Grant support

E. Pereda acknowledges the financial support of the Spanish MINECO (Ministerio de Economía y Competitividad) and MEC (Ministry of Science and Technology) under grants TEC2012-38453-C04-03 and PRX12/00564, respectively. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.