[Endobronchial ultrasound in the diagnosis of malignant pleural mesothelioma]

Rev Mal Respir. 2015 Sep;32(7):750-4. doi: 10.1016/j.rmr.2014.12.009. Epub 2015 Jun 9.
[Article in French]


The diagnosis of malignant pleural mesothelioma relies mostly on the pathological examination of pleural samples, validated by a panel of experts and generally obtained during medical or surgical thoracoscopy performed for the management of an exudative pleural effusion. In the absence of pleural effusion (dry-type mesothelioma), the diagnostic approach depends on the features of the lesions (pleural thickness, nodules and/or masses) and their pleural location. Ultrasound and CT-guided needle aspiration represent recognized alternative diagnostic techniques in these situations. We present the case of a patient, presenting a dry-type mesothelioma, whose diagnosis was obtained by endobronchial ultrasound (EBUS)-guided needle aspiration of a pleural mediastinal mass and confirmed by a CT-guided needle aspiration of another pleural mass in close contact with the chest wall. The samples have been compared and show quantitative and qualitative similarities. EBUS represents a minimally invasive alternative diagnostic technique for dry-type mesothelioma, showing thickness of the mediastinal pleura in contact with a central airway or when thoracoscopy, which remains the "gold standard" diagnostic approach, is not feasible.

Keywords: Bronchoscopie; Bronchoscopy; Endobronchial ultrasound bronchoscopy; Mésothéliome pleural; Pleura; Pleural mesothelioma; Plèvre; Échoendoscopie.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy, Fine-Needle / methods
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / pathology
  • Male
  • Mesothelioma / diagnostic imaging*
  • Mesothelioma / pathology
  • Mesothelioma, Malignant
  • Pleural Neoplasms / diagnostic imaging*
  • Pleural Neoplasms / pathology
  • Radiography, Thoracic
  • Thoracoscopy / methods
  • Ultrasonography, Interventional