Fast silicon photomultiplier improves signal harvesting and reduces complexity in time-domain diffuse optics
- PMID: 26072763
- DOI: 10.1364/OE.23.013937
Fast silicon photomultiplier improves signal harvesting and reduces complexity in time-domain diffuse optics
Abstract
We present a proof of concept prototype of a time-domain diffuse optics probe exploiting a fast Silicon PhotoMultiplier (SiPM), featuring a timing resolution better than 80 ps, a fast tail with just 90 ps decay time-constant and a wide active area of 1 mm2. The detector is hosted into the probe and used in direct contact with the sample under investigation, thus providing high harvesting efficiency by exploiting the whole SiPM numerical aperture and also reducing complexity by avoiding the use of cumbersome fiber bundles. Our tests also demonstrate high accuracy and linearity in retrieving the optical properties and suitable contrast and depth sensitivity for detecting localized inhomogeneities. In addition to a strong improvement in both instrumentation cost and size with respect to legacy solutions, the setup performances are comparable to those of state-of-the-art time-domain instrumentation, thus opening a new way to compact, low-cost and high-performance time-resolved devices for diffuse optical imaging and spectroscopy.
Similar articles
-
Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy.Biomed Opt Express. 2020 Oct 16;11(11):6389-6412. doi: 10.1364/BOE.400868. eCollection 2020 Nov 1. Biomed Opt Express. 2020. PMID: 33282497 Free PMC article.
-
Probe-hosted silicon photomultipliers for time-domain functional near-infrared spectroscopy: phantom and in vivo tests.Neurophotonics. 2016 Oct;3(4):045004. doi: 10.1117/1.NPh.3.4.045004. Epub 2016 Oct 12. Neurophotonics. 2016. PMID: 27752520 Free PMC article.
-
Time-domain diffuse optics with 8.6 mm2 fast-gated SiPM for extreme light harvesting.Opt Lett. 2021 Jan 15;46(2):424-427. doi: 10.1364/OL.413577. Opt Lett. 2021. PMID: 33449045
-
The silicon photomultiplier: fundamentals and applications of a modern solid-state photon detector.Phys Med Biol. 2020 Aug 21;65(17):17TR01. doi: 10.1088/1361-6560/ab7b2d. Phys Med Biol. 2020. PMID: 32109891 Review.
-
Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.Biomed Eng Lett. 2022 Jul 16;12(3):263-283. doi: 10.1007/s13534-022-00234-y. eCollection 2022 Aug. Biomed Eng Lett. 2022. PMID: 35892029 Free PMC article. Review.
Cited by
-
Kernel Flow: a high channel count scalable time-domain functional near-infrared spectroscopy system.J Biomed Opt. 2022 Jan;27(7):074710. doi: 10.1117/1.JBO.27.7.074710. J Biomed Opt. 2022. PMID: 35043610 Free PMC article.
-
The Potential Role of fNIRS in Evaluating Levels of Consciousness.Front Hum Neurosci. 2021 Jul 8;15:703405. doi: 10.3389/fnhum.2021.703405. eCollection 2021. Front Hum Neurosci. 2021. PMID: 34305558 Free PMC article.
-
Silicon Photomultipliers for Deep Tissue Cerenkov Emission Detection During External Beam Radiotherapy.IEEE Photonics J. 2019 Aug;11(4):6802316. doi: 10.1109/jphot.2019.2931845. Epub 2019 Jul 29. IEEE Photonics J. 2019. PMID: 33747354 Free PMC article.
-
Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy.Biomed Opt Express. 2020 Oct 16;11(11):6389-6412. doi: 10.1364/BOE.400868. eCollection 2020 Nov 1. Biomed Opt Express. 2020. PMID: 33282497 Free PMC article.
-
Optimizing sensitivity and dynamic range of silicon photomultipliers for frequency-domain near infrared spectroscopy.Biomed Opt Express. 2020 Sep 1;11(9):5373-5387. doi: 10.1364/BOE.401439. eCollection 2020 Sep 1. Biomed Opt Express. 2020. PMID: 33014621 Free PMC article.
LinkOut - more resources
Full Text Sources
Other Literature Sources
